Possibia

216268

Last Update Posted: 2006-02-09

Recruiting status is unknown

All Genders

accepted

6 months-12 Years

200 Estimated Participants

No Expanded Access

Interventional Study

Does not accept healthy volunteers

Treatment of Japanese Encephalitis

Japanese encephalitis is the single largest cause of viral encephalitis in the world today. It occurs in yearly post monsoon outbreaks in Uttar Pradesh and other parts of India and south east Asia. There is presently no antiviral drug of proven benefit for this illness and treatment is mostly supportive. The drug Ribavirin is already in the market in use for other indications. It has been found useful in West Nile encephalitis and various hemorrhagic fevers caused by related arboviruses. This is a double blind placebo of Ribavirin in Japanese encephalitis. To the best of our knowledge, this is the first such trial in the world. The study hypothesis is that children treated with ribavirin will be no different from those getting placebo in terms of mortality, length of hospital stay, days to return to consciousness and oral feeds, days to become afebrile and convulsion free and in 3 month sequelae rate.

Eligibility

Relevant conditions:

Japanese Encephalitis

If you aren't sure if you meet the criteria above speak to your healthcare professional. Criteria may be updated but not reflected here, do not hesitate to contact the trial if you think are close to fitting criteria.

locations

Contact Information

Overall Contact

Rashmi Kumar, MD

rashmik2005@gmail.com

91-522-2374777

Data sourced from ClinicalTrials.gov