2253732
Last Update Posted: 2018-04-17
Recruiting has ended
All Genders accepted | 60 Years-85 Years |
30 Estimated Participants | No Expanded Access |
Interventional Study | Accepts healthy volunteers |
Skeletal Muscle as a Mediator of Exercise Induced Effects on Metabolism & Cognitive Function: Role for Myokines & miRNAs
The purpose of this study is to determine specific changes in muscle secretory profile (myokines, miRNA) in association with neurodegenerative disease progression and metabolic dysfunction. Next the investigators would like to determine the shift in the muscle secretory activity induced by regular exercise intervention, which the investigators think could be translated into the beneficial changes in clinical phenotypes, determined by neuroimaging, cognitive function tests and metabolic phenotyping.
Standard Operating Procedures for patient recruitment, data collection, data management, data analysis routinely used in University Hospital Bratislava and in Institute of Experimental Endocrinology Slovak Academy of Sciences will be employed.
Statistical analysis will be employed to address the primary and secondary objectives, as specified in the study protocol.
Eligibility
Relevant conditions:
Mild Cognitive Impairment
Alzheimer Disease
Parkinson Disease
Healthy Volunteers
If you aren't sure if you meet the criteria above speak to your healthcare professional. Criteria may be updated but not reflected here, do not hesitate to contact the trial if you think are close to fitting criteria.
locations
Contact Information
Overall Contact
No valid contacts available
Data sourced from ClinicalTrials.gov