Possibia

2271802

Last Update Posted: 2014-10-22

Recruiting has ended

All Genders

accepted

18 Years +

12 Estimated Participants

No Expanded Access

Interventional Study

Does not accept healthy volunteers

Effect of a Butyrate Enema on the Systemic Concentration of Short Chain Fatty Acids

In this placebo-controlled randomized parallel study the effects of a butyrate enema on plasma short-chain fatty acids (SCFA) concentrations and fluxes from portal drained viscera, liver and the splanchnic area are investigated

Patients undergoing upper abdominal surgery are included. During surgery they receive a butyrate enema or placebo enema. Before and after rectal administration, plasma samples are taken from several veins and arteries to analyse SCFA concentrations and fluxes from portal drained viscera, liver and the splanchnic area.

Eligibility

Relevant conditions:

SCFA Metabolism

If you aren't sure if you meet the criteria above speak to your healthcare professional. Criteria may be updated but not reflected here, do not hesitate to contact the trial if you think are close to fitting criteria.

locations

Data sourced from ClinicalTrials.gov