Possibia

2567942

Last Update Posted: 2021-04-20

Recruiting has ended

All Genders

accepted

20 Years +

153 Estimated Participants

No Expanded Access

Interventional Study

Does not accept healthy volunteers

Assessment of the Anesthetic Effect on the Activity of Immune Cell in Patient With Colon Cancer

Anesthetics agents has variety inflammation during the cancer surgery. This perioperative inflammation can influence to cancer metastasis or recurrence.

The purpose of this study is to prove the variation of immune cell activity between preoperative and postoperative period.

The patients were allocated randomly to receive propofol or sevoflurane. Also, a total of 18ml of blood sample was obtained for total 3 times in consecutive order.

  1. immediate before anesthesia induction
  2. postoperative 1 hours
  3. postoperative 24 hours

Serum in blood will be obtained and activity of helper T cell, natural killer cell and level of serum cytokine will be evaluated by flow cytometry or enzyme-linked immunosorbent assay

Eligibility

Relevant conditions:

Colon Cancer

If you aren't sure if you meet the criteria above speak to your healthcare professional. Criteria may be updated but not reflected here, do not hesitate to contact the trial if you think are close to fitting criteria.

locations

Data sourced from ClinicalTrials.gov