2966392
Last Update Posted: 2020-05-29
Recruiting has ended
All Genders accepted | 18 Years + |
600 Estimated Participants | No Expanded Access |
Interventional Study | Does not accept healthy volunteers |
Continuous Endotracheal Cuff Pressure Control to Prevent Ventilator Associated Respiratory Infections
The purpose of the study is to determine whether automated cuff pressure control results in a reduction in the proportion of patients developing ventilator associated respiratory infections during their stay in intensive care.
The proposed study is a randomized controlled trial of tracheal cuff pressure control using continuous control via an automated electronic device as compared with intermittent pressure control for the prevention of ventilator associated respiratory infection in ICU.
The study will be conducted at multiple sites in Vietnam. Recruitment will be for 18 months at all centers. Patients experiencing any hospital acquired infection whilst at risk of Ventilator Associated Respiratory Infections will be evaluated in using a standardised investigation protocol to identify cases of VARI and other hospital acquired infections (HAI)s. Assessment of VARI will be based on published criteria and carried out by an endpoint review committee independent of patient care and blinded to the allocation of the patient. Antibiotic use data and duration of stay will be important secondary outcome measures.
Eligibility
Relevant conditions:
Mechanical Ventilation Complication
Tracheal Intubation Morbidity
Ventilator-Associated Pneumonia
Hospital Acquired Infection
If you aren't sure if you meet the criteria above speak to your healthcare professional. Criteria may be updated but not reflected here, do not hesitate to contact the trial if you think are close to fitting criteria.
locations
Data sourced from ClinicalTrials.gov