Possibia

3163238

Last Update Posted: 2018-07-09

Recruiting status is unknown

All Genders

accepted

1 Years-12 Years

60 Estimated Participants

No Expanded Access

Interventional Study

Does not accept healthy volunteers

Dexmedetomidine and the Inflammatory Response in Pediatric Cardiac Surgery

Cardiopulmonary bypass-assisted surgery initiates a systemic inflammatory response induced by extrinsic (e.g. anesthesia, contact activation within the extracorporeal circuit, endotoxemia) and intrinsic (e.g. tissue damage, endothelial cell activation, ischemia-reperfusion injury of myocardium) factors. This may either be mild or lead to a more severe clinical condition. Inflammation after pediatric open heart surgery is a parameter affecting also duration of mechanical ventilatory support. Dexmedetomidine use was associated with a reduced increase in plasma IL-1, IL-6, TNF-a, and INF-g levels

Dexmedetomidine will be used during Cardiopulmonary bypass-assisted surgery for pediatric cardiac surgery

Eligibility

Relevant conditions:

Cardiac Surgical Procedures

If you aren't sure if you meet the criteria above speak to your healthcare professional. Criteria may be updated but not reflected here, do not hesitate to contact the trial if you think are close to fitting criteria.

locations

Contact Information

Overall Contact

Sayed K Abd-Elshafy, MD

sayed_k_72@yahoo.com

0882293592

Data sourced from ClinicalTrials.gov