3203642
Last Update Posted: 2023-02-06
Recruiting has ended
All Genders accepted | 18 Years-60 Years |
80 Estimated Participants | No Expanded Access |
Interventional Study | Does not accept healthy volunteers |
Study of the Efficacy and Safety of Tesevatinib in Subjects With ADPKD
The goal of the study was to compare and evaluate safety and efficacy of tesevatinib 50 milligrams (mg) versus placebo in participants with autosomal dominant polycystic kidney disease (ADPKD).
Safety and efficacy of 50 mg tesevatinib in comparison to placebo in participants with ADPKD was assessed.
The primary purpose of this study was focused on evaluating the change from Baseline in height-adjusted total kidney volume (htTKV) as measured by magnetic resonance imaging (MRI) at Months 12, 18, and 24, and 30 days post-dose in participants with ADPKD treated with tesevatinib or placebo.
If eligible for the study participation, participants were randomly assigned to either investigational treatment group or placebo group. Treatment group received 50 mg tesevatinib once daily for 24 months and control group received the placebo once daily for 24 months.
Eligibility
Relevant conditions:
Autosomal Dominant Polycystic Kidney
ADPKD
If you aren't sure if you meet the criteria above speak to your healthcare professional. Criteria may be updated but not reflected here, do not hesitate to contact the trial if you think are close to fitting criteria.
locations
Data sourced from ClinicalTrials.gov