Possibia

3320759

Last Update Posted: 2024-03-28

Recruiting

All Genders

accepted

18 Years +

40 Estimated Participants

No Expanded Access

Interventional Study

Does not accept healthy volunteers

Enhancing Recovery in Non-Traumatic Spinal Cord Injury

The investigators have spent the last decade uncovering unique metabolic and functional abnormalities in the brains of patients with spinal cord compression. Degenerative spinal cord compression represents a unique model of reversible spinal cord injury. In the investigator's previous work, they have demonstrated that cortical reorganization and recruitment is associated with metabolic changes in the brains of patients recovering from spinal cord compression and is correlated with recovery and improved neurological scores.

The goal of this study is to combine a rigorous platform of clinical care that includes preoperative evaluation, surgery, and rehabilitation, with state of the art imaging techniques to demonstrate how rehabilitative therapy can increase brain plasticity and recovery of neurological function in patients with spinal cord injury. Neurological function will be carefully evaluated in two groups of patients, those receiving rehabilitation and those not receiving rehabilitation after spine surgery, and will be correlated with the results of advanced imaging.

Eligibility

Relevant conditions:

Spinal Cord Compression

Spinal Cord Injuries

Cervical Spondylosis

Myelopathy Cervical

If you aren't sure if you meet the criteria above speak to your healthcare professional. Criteria may be updated but not reflected here, do not hesitate to contact the trial if you think are close to fitting criteria.

locations

Contact Information

Overall Contact

Sarah Detombe, PhD

sarah.detombe@lhsc.on.ca

5196858500

Data sourced from ClinicalTrials.gov