484
Last Update Posted: 2013-11-26
Recruiting has ended
All Genders accepted | 21 Years-55 Years |
Estimated Participants | No Expanded Access |
Interventional Study | Does not accept healthy volunteers |
Treatment of Hypertension
To determine whether the long-term treatment of essential hypertension without significant target organ disease materially influenced mortality and/or cardiovascular renal morbidity.
BACKGROUND:
This grant-supported, cooperative, fixed-protocol clinical study was initiated in 1966 and followed a cooperative study of the treatment of renal hypertension initiated in 1960 to evaluate the relative efficacy of several recognized drug regimens for reduction of blood pressure. Six centers (USPHS hospitals) and a coordinating center were involved in the trial.
DESIGN NARRATIVE:
Randomized, double-blind, fixed sample. Three hundred and eighty nine eligible patients were assigned to drug therapy consisting of chlorothiazide plus Rauwolfia serpentina or to placebo.
The study completion date listed in this record was inferred from last publication listed in the Citations section of this study record.
Eligibility
Relevant conditions:
Cardiovascular Diseases
Heart Diseases
Hypertension
Vascular Diseases
If you aren't sure if you meet the criteria above speak to your healthcare professional. Criteria may be updated but not reflected here, do not hesitate to contact the study if you think are close to fitting criteria.
locations
Data sourced from ClinicalTrials.gov