Possibia

738348

Last Update Posted: 2012-06-08

Recruiting has ended

All Genders

accepted

Under

50 Estimated Participants

No Expanded Access

Interventional Study

Accepts healthy volunteers

Effect of Perioperative Sivelstat Administration for Liver Resection

It is reported that sivelstat improved and preserved the postoperative renal function in the orthopedic management. Moreover because sivelstat reduced the migration of neutrophil, it improved acute lung injury. During liver resection, Pringle maneuver, clamping the hepatoduodenal ligament, was performed. Pringle maneuver causes reperfusion injury of the liver. We have a hypothesis that sivelstat prevent the warm shock of reperfusion injury of the liver by Pringle maneuver.

Whether the incidence of postoperative morbidities, such as liver failure, renal failure, or congestive heart failure, was reduced by administration of perioperative sivelstat.

Eligibility

Relevant conditions:

Liver Diseases

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locations

Contact Information

Overall Contact

No valid contacts available

Data sourced from ClinicalTrials.gov