742118
Last Update Posted: 2015-09-30
Recruiting status is unknown
All Genders accepted | 18 Years-70 Years |
200 Estimated Participants | No Expanded Access |
Interventional Study | Does not accept healthy volunteers |
Effects of the Soluble Mediators of Mastocytes on the Intestinal Epithelial Barrier and of the Enteric Nervous System During the Syndrome of the Irritable Bowel
Patients with irritable bowel syndrome (IBS) have increased intestinal permeability. In addition, mucosal soluble mediators are involved in the pathophysiology of pain in IBS. The investigators aimed to investigate:
- paracellular permeability in colonic biopsies of IBS patient
- the ability of soluble factors from colonic biopsies to reproduce in vitro these alterations
Eligibility
Relevant conditions:
Irritable Bowel Syndrome
If you aren't sure if you meet the criteria above speak to your healthcare professional. Criteria may be updated but not reflected here, do not hesitate to contact the study if you think are close to fitting criteria.
locations
Contact Information
Overall Contact
Thierry PICHE, PhD
piche.t@chu-nice.fr
Data sourced from ClinicalTrials.gov