746044
Last Update Posted: 2009-05-15
Recruiting has ended
All Genders accepted | 18 Years-85 Years |
40 Estimated Participants | No Expanded Access |
Observational Study | Accepts healthy volunteers |
Measurement of MRP2 Function Using Urinary Coproporphyrins
Human Multidrug Related Protein 2 (MRP2) excretes several drugs and could therefore modulate their elimination. Individual's MRP2 activity is under genetic control. Thus it would be very useful to get an easily measurable biomarker reflecting individual's MRP2 activity. We aimed to investigate the ratio of urinary coproporphyrins I and III (UCP(I/I+III), known to be increased in patients with mutations in MRP2/ABCC2 gene.
Eligibility
Relevant conditions:
Healthy Subjects
If you aren't sure if you meet the criteria above speak to your healthcare professional. Criteria may be updated but not reflected here, do not hesitate to contact the study if you think are close to fitting criteria.
locations
Data sourced from ClinicalTrials.gov