748514
Last Update Posted: 2008-10-07
Recruiting has ended
Males accepted | 43 Years-78 Years |
266 Estimated Participants | No Expanded Access |
Observational Study | Does not accept healthy volunteers |
A Capsular Incision and Biochemical Recurrence After Radical Perineal Prostatectomy
To evaluate the impact of capsular incisions on biochemical recurrence (BCR) and the potential risk factors of capsular incisions.
The pathological classification of the prostate following radical prostatectomy provides important prognostic information; an accurate pathology report is the cornerstone to cancer treatment and follow-up. In addition to the preoperative serum PSA, Gleason score on pathology specimens, seminal vesicle invasion and lymph node status, and a positive surgical margin with extraprostatic extension (EPE) are significant predictors of clinical and biochemical recurrence. However, the prognostic implication of a capsular incision, a tumor extending to the inked margins without a histologically documented EPE, remains to be defined.
Eligibility
Relevant conditions:
Radical Perineal Prostatectomy
If you aren't sure if you meet the criteria above speak to your healthcare professional. Criteria may be updated but not reflected here, do not hesitate to contact the study if you think are close to fitting criteria.
locations
Data sourced from ClinicalTrials.gov